Peptide Libraray

Mastoparan

General Information

DCTPep ID DCTPep02656

Peptide Name Mastoparan

Sequence INLKALAALAKKIL

Sequence Length 14

UniProt ID Not available

PubChem CID Not available

Origin Vespula lewisii

Type Synthetic peptide

Classification

ACP Tumor active peptide Cell-penetrating peptides

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
HeLa	Human papillomavirus-related endocervical adenocarcinoma	IC50=5 µM	MTT assay	20 h	1

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure DCTPep02656

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Ethylamine

Other Modification None

Chiral L

Physicochemical Information

Formula C70H130N18O16

Absent amino acids CDEFGHMPQRSTVWY

Theoretical pI 10.30

Acidic residues 0

Basic residues 3

Polar residues 1

Molecular weight (Average) 1479.91

Molecular weight (Monoisotopic) 1478.99

Common amino acids AL

Net charge 3

Instability index (II) 10.91

Aliphatic index 195.71

Grand average of hydropathicity (GRAVY) 1.157

Half Life
20 hours (mammalian reticulocytes, in vitro).
30 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).

Extinction coefficients
Should not be visible by UV spectrophotometry.

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 26114809

Title Sequence-activity relationship, and mechanism of action of mastoparan analogues against extended-drug resistant Acinetobacter baumannii

Doi 10.1016/j.ejmech.2015.06.016

Year 2015

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available