This work is licensed under a Creative Commons Attribution 4.0 International License.
Vitri B
General Information
DCTPep ID DCTPep03439
Peptide Name Vitri B
Sequence GYPICGESCVGGICNIPGCSCSWPVCTTN
Sequence Length 29
UniProt ID Not available
PubChem CID Not available
Origin Plantae
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep03439
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C121H186N32O40S6
Absent amino acids ADFHKLMQR
Theoretical pI 4.00
Acidic residues 1
Basic residues 0
Polar residues 19
Molecular weight (Average) 2921.36
Molecular weight (Monoisotopic) 2919.18
Common amino acids C
Net charge -1
Instability index (II) 60.17
Aliphatic index 60.34
Grand average of hydropathicity (GRAVY) 0.469
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 7365
Abs 0.1% (=1 g/l) 2.521, assuming all pairs of Cys residues form cystines
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 2.393, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 20580652
Title Isolation and characterization of cytotoxic cyclotides from Viola tricolor
Doi Not available
Year 2010
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 2493
This work is licensed under a Creative Commons Attribution 4.0 International License.