DCTPep ID  DCTPep03450

Peptide Name   K6L2W3

Sequence  KLWKKWKKWLK

Sequence Length  11

UniProt ID  Not available

PubChem CID  71588901 

Origin  Synthetic

Type  Synthetic peptide

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L

Grand average of hydropathicity (GRAVY)  -1.682

Half Life 
  1.3 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  3 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 16500
  Abs 0.1% (=1 g/l) 10.496

Amino acid distribution

Literature 1

Pubmed ID 30447380

Title  Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators

Doi Not available

Year  2019

Literature 2

Pubmed ID 28105725

Title  Antifungal peptides: a potential new class of antifungals for treating vulvovaginal candidiasis caused by fluconazole-resistant Candida albicans

Doi Not available

Year  2017

Literature 3

Pubmed ID 19285481

Title  Cell specificity, anti-inflammatory activity, and plausible bactericidal mechanism of designed Trp-rich model antimicrobial peptides

Doi Not available

Year  2009

Literature 4

Pubmed ID 20621141

Title  Mammalian cell toxicity and candidacidal mechanism of Arg- or Lys-containing Trp-rich model antimicrobial peptides and their d-enantiomeric peptides

Doi Not available

Year  2010

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available

DBAASP ID  2820