Halictine-1/6, HAL-1/6

General Information


DCTPep ID  DCTPep03454

Peptide Name   Halictine-1/6, HAL-1/6

Sequence  GMWSKILGHLIK

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C65H107N17O14S1

Absent amino acids  ACDEFNPQRTVY

Theoretical pI  10.00

Acidic residues  0

Basic residues  3

Polar residues  3

Molecular weight (Average)  1382.73

Molecular weight (Monoisotopic)  1381.79

Common amino acids  GIKL

Net charge  3

Instability index (II)  11.07

Aliphatic index  130.00

Grand average of hydropathicity (GRAVY)  0.417

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 5500
  Abs 0.1% (=1 g/l) 3.978

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 22100226

Title  Toxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells

Doi Not available

Year  2012

Literature 2

Pubmed ID 20198492

Title  Novel antimicrobial peptides from the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs

Doi Not available

Year  2010

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  3267

DCTPep is developed by Dr.Zheng's team.