Halictine-1/6, HAL-1/6
General Information
DCTPep ID DCTPep03454
Peptide Name Halictine-1/6, HAL-1/6
Sequence GMWSKILGHLIK
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C65H107N17O14S1
Absent amino acids ACDEFNPQRTVY
Theoretical pI 10.00
Acidic residues 0
Basic residues 3
Polar residues 3
Molecular weight (Average) 1382.73
Molecular weight (Monoisotopic) 1381.79
Common amino acids GIKL
Net charge 3
Instability index (II) 11.07
Aliphatic index 130.00
Grand average of hydropathicity (GRAVY) 0.417
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 3.978
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22100226
Title Toxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells
Doi Not available
Year 2012
Literature 2
Pubmed ID 20198492
Title Novel antimicrobial peptides from the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs
Doi Not available
Year 2010
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 3267