This work is licensed under a Creative Commons Attribution 4.0 International License.
Esculentin-2CHa (1-30)
General Information
DCTPep ID DCTPep03469
Peptide Name Esculentin-2CHa (1-30)
Sequence GFSSIFRGVAKFASKGLGKDLAKLGVDLVA
Sequence Length 30
UniProt ID D3UA61
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep03469
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C141H231N37O38
Absent amino acids CEHMNPQTWY
Theoretical pI 10.00
Acidic residues 2
Basic residues 5
Polar residues 8
Molecular weight (Average) 3052.61
Molecular weight (Monoisotopic) 3050.73
Common amino acids G
Net charge 3
Instability index (II) -0.24
Aliphatic index 107.33
Grand average of hydropathicity (GRAVY) 0.547
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23159562
Title Esculentin-2CHa: a host-defense peptide with differential cytotoxicity against bacteria, erythrocytes and tumor cells
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 4388
This work is licensed under a Creative Commons Attribution 4.0 International License.