DCTPep ID  DCTPep03485

Peptide Name   Bactenecin-7 (1-35), Bac-7 (1-35)

Sequence  RRIRPRPPRLPRPRPRPLPFPRPGPRPIPRPLPFP

Sequence Length  35

UniProt ID  P19661 

PubChem CID  16130514 

Origin  Synthetic

Type  Synthetic peptide

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

PDB ID  Not available

Predicted Structure  DCTPep03485

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L

Grand average of hydropathicity (GRAVY)  -1.414

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  2 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution

Literature 1

Pubmed ID 33036159

Title  Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens

Doi Not available

Year  2020

Literature 2

Pubmed ID 29526712

Title  The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome

Doi Not available

Year  2018

Literature 3

Pubmed ID 28137800

Title  The Mechanism of Killing by the Proline-Rich Peptide Bac7(1-35) against Clinical Strains of Pseudomonas aeruginosa Differs from That against Other Gram-Negative Bacteria

Doi Not available

Year  2017

Literature 4

Pubmed ID 15572192

Title  Antimicrobial activity of Bac7 fragments against drug-resistant clinical isolates

Doi Not available

Year  2004

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available

DBAASP ID  5243