Bactenecin-7 (1-23)
General Information
DCTPep ID DCTPep03486
Peptide Name Bactenecin-7 (1-23)
Sequence RRIRPRPPRLPRPRPRPLPFPRP
Sequence Length 23
UniProt ID P19661
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep03486
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C131H222N50O24
Absent amino acids ACDEGHKMNQSTVWY
Theoretical pI 12.90
Acidic residues 0
Basic residues 9
Polar residues 0
Molecular weight (Average) 2881.52
Molecular weight (Monoisotopic) 2879.77
Common amino acids P
Net charge 9
Instability index (II) 106.91
Aliphatic index 50.87
Grand average of hydropathicity (GRAVY) -1.809
Half Life
1 hours (mammalian reticulocytes, in vitro).
2 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 35578204
Title Optimization of the antimicrobial peptide Bac7 by deep mutational scanning
Doi Not available
Year 2022
Literature 2
Pubmed ID 25525837
Title Effect of size and N-terminal residue characteristics on bacterial cell penetration and antibacterial activity of the proline-rich peptide Bac7
Doi Not available
Year 2015
Literature 3
Pubmed ID 15572192
Title Antimicrobial activity of Bac7 fragments against drug-resistant clinical isolates
Doi Not available
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 5245