Buforin-2 (5-13)[17-20]2
General Information
DCTPep ID DCTPep03493
Peptide Name Buforin-2 (5-13)[17-20]2
Sequence RAGLQFPVGRLLRRLLR
Sequence Length 17
UniProt ID P55897
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep03493
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C91H161N33O19
Absent amino acids CDEHIKMNSTWY
Theoretical pI 12.60
Acidic residues 0
Basic residues 5
Polar residues 2
Molecular weight (Average) 2021.49
Molecular weight (Monoisotopic) 2020.26
Common amino acids LR
Net charge 5
Instability index (II) 98.17
Aliphatic index 137.65
Grand average of hydropathicity (GRAVY) -0.035
Half Life
1 hours (mammalian reticulocytes, in vitro).
2 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23776609
Title A cancer specific cell-penetrating peptide, BR2, for the efficient delivery of an scFv into cancer cells
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 5466