Buforin-2 (5-13)[17-20]2

General Information


DCTPep ID  DCTPep03493

Peptide Name   Buforin-2 (5-13)[17-20]2

Sequence  RAGLQFPVGRLLRRLLR

Sequence Length  17

UniProt ID  P55897 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  DCTPep03493

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C91H161N33O19

Absent amino acids  CDEHIKMNSTWY

Theoretical pI  12.60

Acidic residues  0

Basic residues  5

Polar residues  2

Molecular weight (Average)  2021.49

Molecular weight (Monoisotopic)  2020.26

Common amino acids  LR

Net charge  5

Instability index (II)  98.17

Aliphatic index  137.65

Grand average of hydropathicity (GRAVY)  -0.035

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  2 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 23776609

Title  A cancer specific cell-penetrating peptide, BR2, for the efficient delivery of an scFv into cancer cells

Doi Not available

Year  2013

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  5466

DCTPep is developed by Dr.Zheng's team.