This work is licensed under a Creative Commons Attribution 4.0 International License.
Pep27 [E4W][R19W][R22W][R26W]
General Information
DCTPep ID DCTPep03505
Peptide Name Pep27 [E4W][R19W][R22W][R26W]
Sequence MRKWFHNVLSSGQLLADKWPAWDYNWK
Sequence Length 27
UniProt ID Q9S4I9
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep03505
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C160H226N42O38S1
Absent amino acids CEIT
Theoretical pI 9.52
Acidic residues 2
Basic residues 5
Polar residues 6
Molecular weight (Average) 3377.87
Molecular weight (Monoisotopic) 3375.68
Common amino acids W
Net charge 3
Instability index (II) 19.74
Aliphatic index 61.48
Grand average of hydropathicity (GRAVY) -0.796
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 23490
Abs 0.1% (=1 g/l) 6.954
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 16004618
Title Functional and structural characteristics of anticancer peptide Pep27 analogues
Doi Not available
Year 2005
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 5911
This work is licensed under a Creative Commons Attribution 4.0 International License.