Recombinant Pro-Omhep1, Recombinant Hepcidin
General Information
DCTPep ID DCTPep03528
Peptide Name Recombinant Pro-Omhep1, Recombinant Hepcidin
Sequence MGSSHHHHHHSSGLVPRGSHMIPVNGVTELEEAASNDTPVAARHEMSMQSWMMPNHIREKRQSHLSMCSVCCNCCKNYKGCGFCCRF
Sequence Length 87
UniProt ID G4VXJ6
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep03528
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C404H629N133O121S15
Absent amino acids Not Applicable
Theoretical pI 8.19
Acidic residues 6
Basic residues 18
Polar residues 33
Molecular weight (Average) 9766.16
Molecular weight (Monoisotopic) 9759.3
Common amino acids SH
Net charge 12
Instability index (II) 53.96
Aliphatic index 43.68
Grand average of hydropathicity (GRAVY) -0.522
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 7490
Abs 0.1% (=1 g/l) 0.767, assuming all pairs of Cys residues form cystines
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 0.716, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22051539
Title Recombinant medaka (Oryzias melastigmus) pro-hepcidin: Multifunctional characterization
Doi Not available
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 6334