This work is licensed under a Creative Commons Attribution 4.0 International License.
Cyclo(D-Pro-L-Phe), Diketopiperazine (pF)
General Information
DCTPep ID DCTPep03533
Peptide Name Cyclo(D-Pro-L-Phe), Diketopiperazine (pF)
Sequence pF
Sequence Length 2
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: pro1<--->Phe2 (2, 5-diketopiperazine)
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral Mix
Physicochemical Information
Formula Not Applicable
Absent amino acids Not Applicable
Theoretical pI Not Applicable
Acidic residues Not Applicable
Basic residues Not Applicable
Polar residues Not Applicable
Molecular weight (Average) Not Applicable
Molecular weight (Monoisotopic) Not Applicable
Common amino acids Not Applicable
Net charge Not Applicable
Instability index (II) Not Applicable
Aliphatic index Not Applicable
Grand average of hydropathicity (GRAVY) Not Applicable
Half Life
Not Applicable
Extinction coefficients
Not Applicable
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31243345
Title Cyclic tetrapeptides from the marine strain Streptomyces sp PNM-161a with activity against rice and yam phytopathogens
Doi Not available
Year 2019
Literature 2
Pubmed ID 24047443
Title Antimycobacterial activity of cyclic dipeptides isolated from Bacillus sp N strain associated with entomopathogenic nematode
Doi Not available
Year 2014
Literature 3
Pubmed ID 29439550
Title Cytotoxic and Antimicrobial Compounds from the Marine-Derived Fungus, Penicillium Species
Doi Not available
Year 2018
Literature 4
Pubmed ID 14575426
Title dd-diketopiperazines: antibiotics active against Vibrio anguillarum isolated from marine bacteria associated with cultures of Pecten maximus
Doi Not available
Year 2003
Literature 5
Pubmed ID 24622848
Title In vitro antibacterial screening of six proline-based cyclic dipeptides in combination with ?-lactam antibiotics against medically important bacteria
Doi Not available
Year 2014
Literature 6
Pubmed ID 23065379
Title Isolation of proline-based cyclic dipeptides from Bacillus sp N strain associated with rhabditid entomopathogenic nematode and its antimicrobial properties
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 6741
This work is licensed under a Creative Commons Attribution 4.0 International License.