Cyclo(D-Pro-D-Phe), Diketopiperazine (pf)

General Information


DCTPep ID  DCTPep03537

Peptide Name   Cyclo(D-Pro-D-Phe), Diketopiperazine (pf)

Sequence  pf

Sequence Length  2

UniProt ID  Not available

PubChem CID  Not available

Origin  Fungi

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  NCB: pro1<--->phe2 (2, 5-diketopiperazine)

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  D



Physicochemical Information


Formula  Not Applicable

Absent amino acids  Not Applicable

Theoretical pI  Not Applicable

Acidic residues  Not Applicable

Basic residues  Not Applicable

Polar residues  Not Applicable

Molecular weight (Average)  Not Applicable

Molecular weight (Monoisotopic)  Not Applicable

Common amino acids  Not Applicable

Net charge  Not Applicable

Instability index (II)  Not Applicable

Aliphatic index  Not Applicable

Grand average of hydropathicity (GRAVY)  Not Applicable

Half Life 
  Not Applicable

Extinction coefficients 
  Not Applicable

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 29439550

Title  Cytotoxic and Antimicrobial Compounds from the Marine-Derived Fungus, Penicillium Species

Doi Not available

Year  2018

Literature 2

Pubmed ID 14575426

Title  dd-diketopiperazines: antibiotics active against Vibrio anguillarum isolated from marine bacteria associated with cultures of Pecten maximus

Doi Not available

Year  2003

Literature 3

Pubmed ID 23979826

Title  Cyclic dipeptides from rhabditid entomopathogenic nematode-associated Bacillus cereus have antimicrobial activities

Doi Not available

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  6796

DCTPep is developed by Dr.Zheng's team.