Sus scrofa Uncharacterized protein (208-235), SP-E

General Information


DCTPep ID  DCTPep03541

Peptide Name   Sus scrofa Uncharacterized protein (208-235), SP-E

Sequence  DKPKKKPPPPAGPPPPPPPPPGPPPPGP

Sequence Length  28

UniProt ID  F1SQ50 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  DCTPep03541

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C132H202N32O31

Absent amino acids  CEFHILMNQRSTVWY

Theoretical pI  10.00

Acidic residues  1

Basic residues  4

Polar residues  3

Molecular weight (Average)  2733.25

Molecular weight (Monoisotopic)  2731.52

Common amino acids  P

Net charge  3

Instability index (II)  104.4

Aliphatic index  3.57

Grand average of hydropathicity (GRAVY)  -1.746

Half Life 
  1.1 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30046246

Title  The activity of a mammalian proline-rich peptide against Gram-negative bacteria, including drug-resistant strains, relies on a nonmembranolytic mode of action

Doi Not available

Year  2018

Literature 2

Pubmed ID 23274276

Title  Structural and functional studies on a proline-rich peptide isolated from swine saliva endowed with antifungal activity towards Cryptococcus neoformans

Doi Not available

Year  2013

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  7009

DCTPep is developed by Dr.Zheng's team.