Sus scrofa Uncharacterized protein (208-235), SP-E
General Information
DCTPep ID DCTPep03541
Peptide Name Sus scrofa Uncharacterized protein (208-235), SP-E
Sequence DKPKKKPPPPAGPPPPPPPPPGPPPPGP
Sequence Length 28
UniProt ID F1SQ50
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep03541
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C132H202N32O31
Absent amino acids CEFHILMNQRSTVWY
Theoretical pI 10.00
Acidic residues 1
Basic residues 4
Polar residues 3
Molecular weight (Average) 2733.25
Molecular weight (Monoisotopic) 2731.52
Common amino acids P
Net charge 3
Instability index (II) 104.4
Aliphatic index 3.57
Grand average of hydropathicity (GRAVY) -1.746
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30046246
Title The activity of a mammalian proline-rich peptide against Gram-negative bacteria, including drug-resistant strains, relies on a nonmembranolytic mode of action
Doi Not available
Year 2018
Literature 2
Pubmed ID 23274276
Title Structural and functional studies on a proline-rich peptide isolated from swine saliva endowed with antifungal activity towards Cryptococcus neoformans
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 7009