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AMP72
General Information
DCTPep ID DCTPep03557
Peptide Name AMP72
Sequence KGCALVKVRGLTLKVCK
Sequence Length 17
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep03557
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C80H150N24O19S2
Absent amino acids DEFHIMNPQSWY
Theoretical pI 10.07
Acidic residues 0
Basic residues 5
Polar residues 5
Molecular weight (Average) 1816.34
Molecular weight (Monoisotopic) 1815.1
Common amino acids K
Net charge 5
Instability index (II) -17.25
Aliphatic index 125.88
Grand average of hydropathicity (GRAVY) 0.541
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.069, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23893489
Title In vitro activity of novel in silico-developed antimicrobial peptides against a panel of bacterial pathogens
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 7557
This work is licensed under a Creative Commons Attribution 4.0 International License.