VIH-Buforin-2 (5-21), VIH-sh-Buforin
General Information
DCTPep ID DCTPep03568
Peptide Name VIH-Buforin-2 (5-21), VIH-sh-Buforin
Sequence VIHRAGLQFPVGRVHRLLRK
Sequence Length 20
UniProt ID P55897
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep03568
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C107H182N38O22
Absent amino acids CDEMNSTWY
Theoretical pI 12.48
Acidic residues 0
Basic residues 7
Polar residues 2
Molecular weight (Average) 2352.86
Molecular weight (Monoisotopic) 2351.43
Common amino acids R
Net charge 7
Instability index (II) 52.85
Aliphatic index 126.50
Grand average of hydropathicity (GRAVY) -0.055
Half Life
100 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25891844
Title Hybrid peptide ATCUN-sh-Buforin: Influence of the ATCUN charge and stereochemistry on antimicrobial activity
Doi Not available
Year 2015
Literature 2
Pubmed ID 24803240
Title Improved bioactivity of antimicrobial peptides by addition of amino-terminal copper and nickel (ATCUN) binding motifs
Doi Not available
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 7654