This work is licensed under a Creative Commons Attribution 4.0 International License.
Cathelicidin-related peptide, Oh-Cath
General Information
DCTPep ID DCTPep03569
Peptide Name Cathelicidin-related peptide, Oh-Cath
Sequence KFFKKLKNSVKKRAKKFFKKPRVIGVSIPF
Sequence Length 30
UniProt ID B6S2X2
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep03569
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C175H289N47O34
Absent amino acids CDEHMQTWY
Theoretical pI 12.07
Acidic residues 0
Basic residues 12
Polar residues 4
Molecular weight (Average) 3595.51
Molecular weight (Monoisotopic) 3593.23
Common amino acids K
Net charge 12
Instability index (II) 4.33
Aliphatic index 71.33
Grand average of hydropathicity (GRAVY) -0.517
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24637683
Title Therapeutic potential of the antimicrobial peptide OH-CATH30 for antibiotic-resistant Pseudomonas aeruginosa keratitis
Doi Not available
Year 2014
Literature 2
Pubmed ID 20576537
Title Structure-function relationship of king cobra cathelicidin
Doi Not available
Year 2010
Literature 3
Pubmed ID 22491685
Title Efficacy of OH-CATH30 and its analogs against drug-resistant bacteria in vitro and in mouse models
Doi Not available
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 7699
This work is licensed under a Creative Commons Attribution 4.0 International License.