This work is licensed under a Creative Commons Attribution 4.0 International License.
Ep-AMP1
General Information
DCTPep ID DCTPep03586
Peptide Name Ep-AMP1
Sequence CVLIGQRCDNDRGPRCCSGQGNCVPLPFLGGVCAV
Sequence Length 35
UniProt ID Not available
PubChem CID Not available
Origin Plantae
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID 2MFS
Predicted Structure DCTPep03586
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C148H244N48O45S6
Absent amino acids EHKMTWY
Theoretical pI 7.78
Acidic residues 2
Basic residues 3
Polar residues 15
Molecular weight (Average) 3608.22
Molecular weight (Monoisotopic) 3605.66
Common amino acids CG
Net charge 1
Instability index (II) 20.96
Aliphatic index 80.57
Grand average of hydropathicity (GRAVY) 0.280
Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 375
Abs 0.1% (=1 g/l) 0.104, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25821084
Title A Cactus-Derived Toxin-Like Cystine Knot Peptide with Selective Antimicrobial Activity
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 7862
This work is licensed under a Creative Commons Attribution 4.0 International License.