DCTPep ID  DCTPep03594

Peptide Name   Coprisin (22-30)[H23L]

Sequence  LLCIALRKK

Sequence Length  9

UniProt ID  A9XFZ7 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L

Grand average of hydropathicity (GRAVY)  0.878

Half Life 
  5.5 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all pairs of Cys residues form cystines
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution

Literature 1

Pubmed ID 22297233

Title  Effects of the Synthetic peptide coprisin analog peptide, CopA3 in pathogenic microorganisms and mammalian cancer cells

Doi Not available

Year  2012

Literature 2

Pubmed ID 24321546

Title  Synthesis and antimicrobial activity of cysteine-free coprisin nonapeptides

Doi Not available

Year  2014

Literature 3

Pubmed ID 24393527

Title  Structure-activity relationships of the intramolecular disulfide bonds in coprisin, a defensin from the dung beetle

Doi Not available

Year  2014

Literature 4

Pubmed ID 20721297

Title  Isolation and Characterization of a Defensin-Like Peptide (Coprisin) from the Dung Beetle, Copris tripartitus

Doi Not available

Year  2009

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available

DBAASP ID  8070