This work is licensed under a Creative Commons Attribution 4.0 International License.
AaeAP1
General Information
DCTPep ID DCTPep03599
Peptide Name AaeAP1
Sequence FLFSLIPSVIAGLVSAIRN
Sequence Length 19
UniProt ID A0A060QQ43
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C96H157N23O24
Absent amino acids CDEHKMQTWY
Theoretical pI 9.75
Acidic residues 0
Basic residues 1
Polar residues 5
Molecular weight (Average) 2017.44
Molecular weight (Monoisotopic) 2016.18
Common amino acids ILS
Net charge 1
Instability index (II) 24.59
Aliphatic index 164.21
Grand average of hydropathicity (GRAVY) 1.584
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25626077
Title AaeAP1 and AaeAP2: novel antimicrobial peptides from the venom of the scorpion, Androctonus aeneas: structural characterisation, molecular cloning of bioSynthetic peptide precursor-encoding cDNAs and engineering of analogues with enhanced antimicrobial and anticancer activities
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8151
This work is licensed under a Creative Commons Attribution 4.0 International License.