This work is licensed under a Creative Commons Attribution 4.0 International License.
AaeAP2
General Information
DCTPep ID DCTPep03600
Peptide Name AaeAP2
Sequence FLFSLIPSAIAGLVSAIRN
Sequence Length 19
UniProt ID A0A060QMQ0
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C94H153N23O24
Absent amino acids CDEHKMQTWY
Theoretical pI 9.75
Acidic residues 0
Basic residues 1
Polar residues 5
Molecular weight (Average) 1989.39
Molecular weight (Monoisotopic) 1988.15
Common amino acids AILS
Net charge 1
Instability index (II) 24.59
Aliphatic index 154.21
Grand average of hydropathicity (GRAVY) 1.458
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25626077
Title AaeAP1 and AaeAP2: novel antimicrobial peptides from the venom of the scorpion, Androctonus aeneas: structural characterisation, molecular cloning of bioSynthetic peptide precursor-encoding cDNAs and engineering of analogues with enhanced antimicrobial and anticancer activities
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8152
This work is licensed under a Creative Commons Attribution 4.0 International License.