Hc-CATH
General Information
DCTPep ID DCTPep03603
Peptide Name Hc-CATH
Sequence KFFKRLLKSVRRAVKKFRKKPRLIGLSTLL
Sequence Length 30
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C171H300N52O34
Absent amino acids CDEHMNQWY
Theoretical pI 12.61
Acidic residues 0
Basic residues 12
Polar residues 4
Molecular weight (Average) 3628.59
Molecular weight (Monoisotopic) 3626.33
Common amino acids K
Net charge 12
Instability index (II) 25.8
Aliphatic index 113.67
Grand average of hydropathicity (GRAVY) -0.273
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34121235
Title Effectiveness of Cathelicidin Antimicrobial Peptide against Ictalurid Catfish Bacterial Pathogens
Doi Not available
Year 2021
Literature 2
Pubmed ID 26013823
Title Identification and Characterization of the First Cathelicidin from Sea Snakes with Potent Antimicrobial and Anti-inflammatory Activity, and Special Mechanism
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8157