Hc-CATH

General Information


DCTPep ID  DCTPep03603

Peptide Name   Hc-CATH

Sequence  KFFKRLLKSVRRAVKKFRKKPRLIGLSTLL

Sequence Length  30

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C171H300N52O34

Absent amino acids  CDEHMNQWY

Theoretical pI  12.61

Acidic residues  0

Basic residues  12

Polar residues  4

Molecular weight (Average)  3628.59

Molecular weight (Monoisotopic)  3626.33

Common amino acids  K

Net charge  12

Instability index (II)  25.8

Aliphatic index  113.67

Grand average of hydropathicity (GRAVY)  -0.273

Half Life 
  1.3 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  3 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 34121235

Title  Effectiveness of Cathelicidin Antimicrobial Peptide against Ictalurid Catfish Bacterial Pathogens

Doi Not available

Year  2021

Literature 2

Pubmed ID 26013823

Title  Identification and Characterization of the First Cathelicidin from Sea Snakes with Potent Antimicrobial and Anti-inflammatory Activity, and Special Mechanism

Doi Not available

Year  2015

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  8157

DCTPep is developed by Dr.Zheng's team.