Temporin-1Sa [S3K]
General Information
DCTPep ID DCTPep03606
Peptide Name Temporin-1Sa [S3K]
Sequence FLKGIVGMLGKLF
Sequence Length 13
UniProt ID B3KYH4
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C70H115N15O14S1
Absent amino acids ACDEHNPQRSTWY
Theoretical pI 10.00
Acidic residues 0
Basic residues 2
Polar residues 3
Molecular weight (Average) 1422.84
Molecular weight (Monoisotopic) 1421.85
Common amino acids GL
Net charge 2
Instability index (II) -36.48
Aliphatic index 142.31
Grand average of hydropathicity (GRAVY) 1.431
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30669255
Title Comparison of Anti-Viral Activity of Frog Skin Anti-Microbial Peptides Temporin-Sha and [K鲁]SHa to LL-37 and Temporin-Tb against Herpes Simplex Virus Type 1
Doi Not available
Year 2019
Literature 2
Pubmed ID 32132569
Title In vitro and intracellular activities of frog skin temporins against Legionella pneumophila and its eukaryotic hosts
Doi Not available
Year 2020
Literature 3
Pubmed ID Not available
Title Analogues of temporin-SHa and uses thereof
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8203