Temporin-1Sa [S3K]

General Information


DCTPep ID  DCTPep03606

Peptide Name   Temporin-1Sa [S3K]

Sequence  FLKGIVGMLGKLF

Sequence Length  13

UniProt ID  B3KYH4 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C70H115N15O14S1

Absent amino acids  ACDEHNPQRSTWY

Theoretical pI  10.00

Acidic residues  0

Basic residues  2

Polar residues  3

Molecular weight (Average)  1422.84

Molecular weight (Monoisotopic)  1421.85

Common amino acids  GL

Net charge  2

Instability index (II)  -36.48

Aliphatic index  142.31

Grand average of hydropathicity (GRAVY)  1.431

Half Life 
  1.1 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30669255

Title  Comparison of Anti-Viral Activity of Frog Skin Anti-Microbial Peptides Temporin-Sha and [K鲁]SHa to LL-37 and Temporin-Tb against Herpes Simplex Virus Type 1

Doi Not available

Year  2019

Literature 2

Pubmed ID 32132569

Title  In vitro and intracellular activities of frog skin temporins against Legionella pneumophila and its eukaryotic hosts

Doi Not available

Year  2020

Literature 3

Pubmed ID Not available

Title  Analogues of temporin-SHa and uses thereof

Doi Not available

Year  2015

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  8203

DCTPep is developed by Dr.Zheng's team.