This work is licensed under a Creative Commons Attribution 4.0 International License.
Peptide P [L21A]
General Information
DCTPep ID DCTPep03614
Peptide Name Peptide P [L21A]
Sequence KWKSFLKTFKSAKKTVLHTAAKAISS
Sequence Length 26
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C136H224N36O34
Absent amino acids CDEGMNPQRY
Theoretical pI 10.78
Acidic residues 0
Basic residues 8
Polar residues 7
Molecular weight (Average) 2907.5
Molecular weight (Monoisotopic) 2905.69
Common amino acids K
Net charge 8
Instability index (II) 9.82
Aliphatic index 71.54
Grand average of hydropathicity (GRAVY) -0.292
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 1.892
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21252288
Title Studies on mechanism of action of anticancer peptides by modulation of hydrophobicity within a defined structural framework
Doi Not available
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8383
This work is licensed under a Creative Commons Attribution 4.0 International License.