Pa-MAP, Antifreeze peptide analogue
General Information
DCTPep ID DCTPep03620
Peptide Name Pa-MAP, Antifreeze peptide analogue
Sequence HTASDAAAAAALTAANAAAAAAASMA
Sequence Length 26
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C90H149N29O34S1
Absent amino acids CEFGIKPQRVWY
Theoretical pI 5.08
Acidic residues 1
Basic residues 1
Polar residues 5
Molecular weight (Average) 2213.41
Molecular weight (Monoisotopic) 2212.05
Common amino acids A
Net charge 0
Instability index (II) 11.46
Aliphatic index 80.38
Grand average of hydropathicity (GRAVY) 0.888
Half Life
3.5 hours (mammalian reticulocytes, in vitro).
10 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 27161201
Title Linear Antimicrobial Peptides With Activity Against Herpes Simplex Virus 1 and Aichi Virus
Doi Not available
Year 2017
Literature 2
Pubmed ID 23056574
Title Structural and functional characterization of a multifunctional alanine-rich peptide analogue from Pleuronectes americanus
Doi Not available
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8795