Pa-MAP, Antifreeze peptide analogue

General Information


DCTPep ID  DCTPep03620

Peptide Name   Pa-MAP, Antifreeze peptide analogue

Sequence  HTASDAAAAAALTAANAAAAAAASMA

Sequence Length  26

UniProt ID  Q03659  P04002 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C90H149N29O34S1

Absent amino acids  CEFGIKPQRVWY

Theoretical pI  5.08

Acidic residues  1

Basic residues  1

Polar residues  5

Molecular weight (Average)  2213.41

Molecular weight (Monoisotopic)  2212.05

Common amino acids  A

Net charge  0

Instability index (II)  11.46

Aliphatic index  80.38

Grand average of hydropathicity (GRAVY)  0.888

Half Life 
  3.5 hours (mammalian reticulocytes, in vitro).
  10 min (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 27161201

Title  Linear Antimicrobial Peptides With Activity Against Herpes Simplex Virus 1 and Aichi Virus

Doi Not available

Year  2017

Literature 2

Pubmed ID 23056574

Title  Structural and functional characterization of a multifunctional alanine-rich peptide analogue from Pleuronectes americanus

Doi Not available

Year  2012

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  8795

DCTPep is developed by Dr.Zheng's team.