DCTPep ID  DCTPep03623

Peptide Name   Hp1404

Sequence  GILGKLWEGVKSIF

Sequence Length  14

UniProt ID  P0DME6 

PubChem CID  46735191 

Origin  Synthetic

Type  Native peptide

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L

Grand average of hydropathicity (GRAVY)  0.671

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 5500
  Abs 0.1% (=1 g/l) 3.556

Amino acid distribution

Literature 1

Pubmed ID 34073939

Title  Comparative Antimicrobial Activity of Hp404 Peptide and Its Analogs against Acinetobacter baumannii

Doi Not available

Year  2021

Literature 2

Pubmed ID 34022355

Title  Identification of the scorpion venom-derived antimicrobial peptide Hp1404 as a new antimicrobial agent against carbapenem-resistant Acinetobacter baumannii

Doi Not available

Year  2021

Literature 3

Pubmed ID 29379033

Title  Mechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa

Doi Not available

Year  2018

Literature 4

Pubmed ID 24826994

Title  Hp1404, a new antimicrobial peptide from the scorpion Heterometrus petersii

Doi Not available

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available

DBAASP ID  8864