This work is licensed under a Creative Commons Attribution 4.0 International License.
ApoE (133-150)
General Information
DCTPep ID DCTPep03628
Peptide Name ApoE (133-150)
Sequence LRVRLASHLRKLRKRLLR
Sequence Length 18
UniProt ID P02649
PubChem CID 146159074
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C101H190N40O20
Absent amino acids CDEFGIMNPQTWY
Theoretical pI 12.70
Acidic residues 0
Basic residues 9
Polar residues 1
Molecular weight (Average) 2284.88
Molecular weight (Monoisotopic) 2283.51
Common amino acids LR
Net charge 9
Instability index (II) 65.64
Aliphatic index 151.67
Grand average of hydropathicity (GRAVY) -0.556
Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 27028511
Title A new cryptic cationic antimicrobial peptide (AMP) from human apolipoprotein E with anti-bacterial activity and immunomodulatory effects on human cells
Doi Not available
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8921
This work is licensed under a Creative Commons Attribution 4.0 International License.