This work is licensed under a Creative Commons Attribution 4.0 International License.
Protamine
General Information
DCTPep ID DCTPep03629
Peptide Name Protamine
Sequence MPRRRRSSSRPVRRRRRPRVSRRRRRRGGRRR
Sequence Length 32
UniProt ID P69015
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C166H316N92O37S1
Absent amino acids ACDEFHIKLNQTWY
Theoretical pI 13.28
Acidic residues 0
Basic residues 20
Polar residues 6
Molecular weight (Average) 4224.99
Molecular weight (Monoisotopic) 4222.54
Common amino acids R
Net charge 20
Instability index (II) 326.37
Aliphatic index 18.12
Grand average of hydropathicity (GRAVY) -2.766
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25192319
Title Rational design of artificial ?-strand-forming antimicrobial peptides with biocompatible properties
Doi Not available
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8930
This work is licensed under a Creative Commons Attribution 4.0 International License.