Temporin-SHd

General Information


DCTPep ID  DCTPep03639

Peptide Name   Temporin-SHd

Sequence  FLPAALAGIGGILGKLF

Sequence Length  17

UniProt ID  D4YWD0 

PubChem CID  Not available

Origin  Animalia

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C82H132N18O18

Absent amino acids  CDEHMNQRSTVWY

Theoretical pI  8.75

Acidic residues  0

Basic residues  1

Polar residues  4

Molecular weight (Average)  1658.06

Molecular weight (Monoisotopic)  1657

Common amino acids  GL

Net charge  1

Instability index (II)  30.68

Aliphatic index  155.29

Grand average of hydropathicity (GRAVY)  1.653

Half Life 
  1.1 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 23116712

Title  Antibacterial and leishmanicidal activities of temporin-SHd, a 17-residue long membrane-damaging peptide

Doi Not available

Year  2013

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  9469

DCTPep is developed by Dr.Zheng's team.