This work is licensed under a Creative Commons Attribution 4.0 International License.
Temporin-SHf [S5R]
General Information
DCTPep ID DCTPep03643
Peptide Name Temporin-SHf [S5R]
Sequence FFFLRRIF
Sequence Length 8
UniProt ID D4YWD1
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C60H84N14O9
Absent amino acids ACDEGHKMNPQSTVWY
Theoretical pI 12.00
Acidic residues 0
Basic residues 2
Polar residues 0
Molecular weight (Average) 1145.42
Molecular weight (Monoisotopic) 1144.65
Common amino acids F
Net charge 2
Instability index (II) 104.43
Aliphatic index 97.50
Grand average of hydropathicity (GRAVY) 1.312
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26181487
Title Structure-Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 9488
This work is licensed under a Creative Commons Attribution 4.0 International License.