Mastoparan-L [A5I, A8R]

General Information


DCTPep ID  DCTPep03644

Peptide Name   Mastoparan-L [A5I, A8R]

Sequence  INLKILARLAKKIL

Sequence Length  14

UniProt ID  P01514 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C76H143N21O16

Absent amino acids  CDEFGHMPQSTVWY

Theoretical pI  11.26

Acidic residues  0

Basic residues  4

Polar residues  1

Molecular weight (Average)  1607.1

Molecular weight (Monoisotopic)  1606.1

Common amino acids  L

Net charge  4

Instability index (II)  18.61

Aliphatic index  209.29

Grand average of hydropathicity (GRAVY)  0.900

Half Life 
  20 hours (mammalian reticulocytes, in vitro).
  30 min (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 27423268

Title  Selective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan

Doi Not available

Year  2016

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  9494

DCTPep is developed by Dr.Zheng's team.