Mastoparan-L [A5I, A8R]
General Information
DCTPep ID DCTPep03644
Peptide Name Mastoparan-L [A5I, A8R]
Sequence INLKILARLAKKIL
Sequence Length 14
UniProt ID P01514
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C76H143N21O16
Absent amino acids CDEFGHMPQSTVWY
Theoretical pI 11.26
Acidic residues 0
Basic residues 4
Polar residues 1
Molecular weight (Average) 1607.1
Molecular weight (Monoisotopic) 1606.1
Common amino acids L
Net charge 4
Instability index (II) 18.61
Aliphatic index 209.29
Grand average of hydropathicity (GRAVY) 0.900
Half Life
20 hours (mammalian reticulocytes, in vitro).
30 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 27423268
Title Selective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan
Doi Not available
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 9494