General Information
DCTPep ID DCTPep03652
Peptide Name
Sequence KWRRWIRWL
Sequence Length 9
UniProt ID Not available
PubChem CID 49777944
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C69H102N22O10
Absent amino acids ACDEFGHMNPQSTVY
Theoretical pI 12.30
Acidic residues 0
Basic residues 4
Polar residues 0
Molecular weight (Average) 1399.71
Molecular weight (Monoisotopic) 1398.81
Common amino acids RW
Net charge 4
Instability index (II) 213.53
Aliphatic index 86.67
Grand average of hydropathicity (GRAVY) -1.311
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 16500
Abs 0.1% (=1 g/l) 11.788
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30447380
Title Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators
Doi Not available
Year 2019
Literature 2
Pubmed ID 30103288
Title Designing an ultra-short antibacterial peptide with potent activity against Mupirocin-resistant MRSA
Doi Not available
Year 2018
Literature 3
Pubmed ID Not available
Title A Head-to-Head Comparison of the Antimicrobial Activities of 30 Ultra-Short Antimicrobial Peptides Against Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 9589