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TistH
General Information
DCTPep ID DCTPep03658
Peptide Name TistH
Sequence ADMDFTGIAESIIKKIKETNAKPPA
Sequence Length 25
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C119H198N30O38S1
Absent amino acids CHLQRVWY
Theoretical pI 6.26
Acidic residues 4
Basic residues 4
Polar residues 5
Molecular weight (Average) 2689.12
Molecular weight (Monoisotopic) 2687.42
Common amino acids AIK
Net charge 0
Instability index (II) 0.29
Aliphatic index 78.40
Grand average of hydropathicity (GRAVY) -0.360
Half Life
4.4 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 27267248
Title Characterization of TistH, a multifunctional peptide from the scorpion Tityus stigmurus: Structure, cytotoxicity and antimicrobial activity
Doi Not available
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 10358
This work is licensed under a Creative Commons Attribution 4.0 International License.