This work is licensed under a Creative Commons Attribution 4.0 International License.
Distinctin-Like-Peptide-PH, DLP-PH
General Information
DCTPep ID DCTPep03687
Peptide Name Distinctin-Like-Peptide-PH, DLP-PH
Sequence NLVSALIEGRKYLKNVLKKLNRLKEKNKAKNSKENN
Sequence Length 36
UniProt ID Q17UZ0
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C184H324N58O53
Absent amino acids CDFHMPQTW
Theoretical pI 10.36
Acidic residues 3
Basic residues 11
Polar residues 11
Molecular weight (Average) 4196.95
Molecular weight (Monoisotopic) 4194.44
Common amino acids K
Net charge 8
Instability index (II) 19.07
Aliphatic index 97.50
Grand average of hydropathicity (GRAVY) -1.197
Half Life
1.4 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.355
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 29628917
Title Discovery of Distinctin-Like-Peptide-PH (DLP-PH) From the Skin Secretion of Phyllomedusa hypochondrialis, a Prototype of a Novel Family of Antimicrobial Peptide
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 11212
This work is licensed under a Creative Commons Attribution 4.0 International License.