Fusaripeptide A

General Information


DCTPep ID  DCTPep03697

Peptide Name   Fusaripeptide A

Sequence  XAaQyI

Sequence Length  6

UniProt ID  Not available

PubChem CID  139591362 

Origin  Fusarium 

Type  Native peptide

Classification

  

ACP Tumor active peptide Amphiphilic



Activity Information


Cell Line Disease Activity Assay Testing Time Literature
L5178Y Mouse thymic lymphoma IC50=5.71μM MTT assay 72h 1
PC12 Rat brain cancer cell lines IC50=9.55μM MTT assay 72h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Ester bond: N-terminal<--->leu6

N-terminal Modification  3-OH-4-Me-C15

C-terminal Modification  Free

Other Modification  X=Allo-Thr

Chiral  Mix



Physicochemical Information


Formula  Not Applicable

Absent amino acids  Not Applicable

Theoretical pI  Not Applicable

Acidic residues  Not Applicable

Basic residues  Not Applicable

Polar residues  Not Applicable

Molecular weight (Average)  Not Applicable

Molecular weight (Monoisotopic)  Not Applicable

Common amino acids  Not Applicable

Net charge  Not Applicable

Instability index (II)  Not Applicable

Aliphatic index  Not Applicable

Grand average of hydropathicity (GRAVY)  Not Applicable

Half Life 
  Not Applicable

Extinction coefficients 
  Not Applicable

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 28446036

Title  Fusaripeptide A: new antifungal and anti-malarial cyclodepsipeptide from the endophytic fungus Fusarium sp

Doi 10.1080/10286020.2017.1320989

Year  2018

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  11344

DCTPep is developed by Dr.Zheng's team.