[F4R4]

General Information


DCTPep ID  DCTPep03726

Peptide Name   [F4R4]

Sequence  FFFFRRRR

Sequence Length  8

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  NCB: Phe1<--->Arg8

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C60H86N20O9

Absent amino acids  ACDEGHIKLMNPQSTVWY

Theoretical pI  12.48

Acidic residues  0

Basic residues  4

Polar residues  0

Molecular weight (Average)  1231.47

Molecular weight (Monoisotopic)  1230.69

Common amino acids  FR

Net charge  4

Instability index (II)  223.55

Aliphatic index  0.00

Grand average of hydropathicity (GRAVY)  -0.850

Half Life 
  1.1 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30360400

Title  Design, Synthesis, and Evaluation of Amphiphilic Cyclic and Linear Peptides Composed of Hydrophobic and Positively-Charged Amino Acids as Antibacterial Agents

Doi Not available

Year  2018

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  11971

DCTPep is developed by Dr.Zheng's team.