This work is licensed under a Creative Commons Attribution 4.0 International License.
[F4R4]
General Information
DCTPep ID DCTPep03726
Peptide Name [F4R4]
Sequence FFFFRRRR
Sequence Length 8
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: Phe1<--->Arg8
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C60H86N20O9
Absent amino acids ACDEGHIKLMNPQSTVWY
Theoretical pI 12.48
Acidic residues 0
Basic residues 4
Polar residues 0
Molecular weight (Average) 1231.47
Molecular weight (Monoisotopic) 1230.69
Common amino acids FR
Net charge 4
Instability index (II) 223.55
Aliphatic index 0.00
Grand average of hydropathicity (GRAVY) -0.850
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30360400
Title Design, Synthesis, and Evaluation of Amphiphilic Cyclic and Linear Peptides Composed of Hydrophobic and Positively-Charged Amino Acids as Antibacterial Agents
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 11971
This work is licensed under a Creative Commons Attribution 4.0 International License.