This work is licensed under a Creative Commons Attribution 4.0 International License.
Hemagglutinin (347-367)[E4G,E7A]-Tat (48-60); N-E5L-Tat (48-60)
General Information
DCTPep ID DCTPep03736
Peptide Name Hemagglutinin (347-367)[E4G,E7A]-Tat (48-60); N-E5L-Tat (48-60)
Sequence GLLEALAELLEGRKKRRQRRRPPQ
Sequence Length 24
UniProt ID D2DUQ8
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C123H220N46O33
Absent amino acids CDFHIMNSTVWY
Theoretical pI 11.71
Acidic residues 3
Basic residues 8
Polar residues 2
Molecular weight (Average) 2871.39
Molecular weight (Monoisotopic) 2869.7
Common amino acids R
Net charge 5
Instability index (II) 126.87
Aliphatic index 89.58
Grand average of hydropathicity (GRAVY) -1.404
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 27713223
Title Fusion of a Short HA2-Derived Peptide Sequence to Cell-Penetrating Peptides Improves Cytosolic Uptake, but Enhances Cytotoxic Activity
Doi Not available
Year 2009
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12032
This work is licensed under a Creative Commons Attribution 4.0 International License.