This work is licensed under a Creative Commons Attribution 4.0 International License.
PKIL+L39e (4-18)[P6I,K10I], PaDBS1R1
General Information
DCTPep ID DCTPep03739
Peptide Name PKIL+L39e (4-18)[P6I,K10I], PaDBS1R1
Sequence PKILNKILGKILRLAAAFK
Sequence Length 19
UniProt ID Q8ZTX6
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C101H179N27O21
Absent amino acids CDEHMQSTVWY
Theoretical pI 11.33
Acidic residues 0
Basic residues 5
Polar residues 2
Molecular weight (Average) 2107.7
Molecular weight (Monoisotopic) 2106.38
Common amino acids KL
Net charge 5
Instability index (II) 36.7
Aliphatic index 159.47
Grand average of hydropathicity (GRAVY) 0.595
Half Life
>20 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
? (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30463701
Title Fast and potent bactericidal membrane lytic activity of PaDBS1R1, a novel cationic antimicrobial peptide
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12113
This work is licensed under a Creative Commons Attribution 4.0 International License.