This work is licensed under a Creative Commons Attribution 4.0 International License.
Nicomicin-1 (1-17)
General Information
DCTPep ID DCTPep03754
Peptide Name Nicomicin-1 (1-17)
Sequence GFWSSVWDGAKNVGTAI
Sequence Length 17
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C83H119N21O24
Absent amino acids CEHLMPQRY
Theoretical pI 5.84
Acidic residues 1
Basic residues 1
Polar residues 7
Molecular weight (Average) 1794.98
Molecular weight (Monoisotopic) 1793.87
Common amino acids G
Net charge 0
Instability index (II) 5.76
Aliphatic index 68.82
Grand average of hydropathicity (GRAVY) 0.182
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 6.128
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30360541
Title Novel Antimicrobial Peptides from the Arctic Polychaeta Nicomache minor Provide New Molecular Insight into Biological Role of the BRICHOS Domain
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12237
This work is licensed under a Creative Commons Attribution 4.0 International License.