This work is licensed under a Creative Commons Attribution 4.0 International License.
Pb-CATH4 (110-133)
General Information
DCTPep ID DCTPep03763
Peptide Name Pb-CATH4 (110-133)
Sequence TRSRWRRFIRGAGRFARRYGWRIA
Sequence Length 24
UniProt ID A0A2P1AGE8
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C137H215N53O28
Absent amino acids CDEHKLMNPQV
Theoretical pI 12.54
Acidic residues 0
Basic residues 9
Polar residues 6
Molecular weight (Average) 3052.55
Molecular weight (Monoisotopic) 3050.7
Common amino acids R
Net charge 9
Instability index (II) 98.9
Aliphatic index 45.00
Grand average of hydropathicity (GRAVY) -1.096
Half Life
7.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 12490
Abs 0.1% (=1 g/l) 4.092
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28630199
Title Genomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity
Doi Not available
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12376
This work is licensed under a Creative Commons Attribution 4.0 International License.