This work is licensed under a Creative Commons Attribution 4.0 International License.
Phylloseptin-PBa2, Phylloseptin-PBu
General Information
DCTPep ID DCTPep03764
Peptide Name Phylloseptin-PBa2, Phylloseptin-PBu
Sequence FLSLLPHIASGIASLVSKF
Sequence Length 19
UniProt ID A0A2K4P1U8
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C96H154N22O24
Absent amino acids CDEMNQRTWY
Theoretical pI 8.76
Acidic residues 0
Basic residues 2
Polar residues 5
Molecular weight (Average) 2000.41
Molecular weight (Monoisotopic) 1999.15
Common amino acids LS
Net charge 2
Instability index (II) 38.27
Aliphatic index 148.95
Grand average of hydropathicity (GRAVY) 1.332
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30612735
Title Phylloseptin-PBa1, -PBa2, -PBa3: Three novel antimicrobial peptides from the skin secretion of Burmeister's leaf frog (Phyllomedusa burmeisteri)
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12382
This work is licensed under a Creative Commons Attribution 4.0 International License.