Phylloseptin-PBa1, Phylloseptin-PBu

General Information


DCTPep ID  DCTPep03765

Peptide Name   Phylloseptin-PBa1, Phylloseptin-PBu

Sequence  FLSLIPHIASGIASLVKNF

Sequence Length  19

UniProt ID  A0A5B7LGG0 

PubChem CID  Not available

Origin  Animalia

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C97H155N23O24

Absent amino acids  CDEMQRTWY

Theoretical pI  8.76

Acidic residues  0

Basic residues  2

Polar residues  5

Molecular weight (Average)  2027.44

Molecular weight (Monoisotopic)  2026.16

Common amino acids  ILS

Net charge  2

Instability index (II)  17.19

Aliphatic index  148.95

Grand average of hydropathicity (GRAVY)  1.226

Half Life 
  1.1 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30612735

Title  Phylloseptin-PBa1, -PBa2, -PBa3: Three novel antimicrobial peptides from the skin secretion of Burmeister's leaf frog (Phyllomedusa burmeisteri)

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  12390

DCTPep is developed by Dr.Zheng's team.