Flower-specific gamma-thionin, ZmD32

General Information


DCTPep ID  DCTPep03821

Peptide Name   Flower-specific gamma-thionin, ZmD32

Sequence  RTCQSQSHRFRGPCLRRSNCANVCRTEGFPGGRCRGFRRRCFCTTHC

Sequence Length  47

UniProt ID  B6SJ49 

PubChem CID  Not available

Origin  Plantae

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  6DMZ 

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C220H356N88O61S8

Absent amino acids  DIKMWY

Theoretical pI  11.03

Acidic residues  1

Basic residues  13

Polar residues  22

Molecular weight (Average)  5466.28

Molecular weight (Monoisotopic)  5462.52

Common amino acids  R

Net charge  12

Instability index (II)  97.01

Aliphatic index  16.60

Grand average of hydropathicity (GRAVY)  -0.911

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  2 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 500
  Abs 0.1% (=1 g/l) 0.091, assuming all pairs of Cys residues form cystines
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31031739

Title  Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  13150

DCTPep is developed by Dr.Zheng's team.