NN2_0018

General Information


DCTPep ID  DCTPep03822

Peptide Name   NN2_0018

Sequence  YLARAIRRTLARLLL

Sequence Length  15

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C82H147N27O18

Absent amino acids  CDEFGHKMNPQSVW

Theoretical pI  12.00

Acidic residues  0

Basic residues  4

Polar residues  2

Molecular weight (Average)  1799.24

Molecular weight (Monoisotopic)  1798.14

Common amino acids  L

Net charge  4

Instability index (II)  47.52

Aliphatic index  176.00

Grand average of hydropathicity (GRAVY)  0.593

Half Life 
  2.8 hours (mammalian reticulocytes, in vitro).
  10 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 0.828

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 29259134

Title  Computational antimicrobial peptide design and evaluation against multidrug-resistant clinical isolates of bacteria

Doi Not available

Year  2018

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  13184

DCTPep is developed by Dr.Zheng's team.