DCTPep ID  DCTPep03842

Peptide Name   Arenicin-1 [W2,21F]

Sequence  RFCVYAYVRVRGVLVRYRRCF

Sequence Length  21

UniProt ID  Q5SC60 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  Cys3<--->Cys20

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L

Grand average of hydropathicity (GRAVY)  0.281

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  2 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 4595
  Abs 0.1% (=1 g/l) 1.713, assuming all pairs of Cys residues form cystines
  Ext. coefficient 4470
  Abs 0.1% (=1 g/l) 1.667, assuming all Cys residues are reduced

Amino acid distribution

Literature 1

Pubmed ID 31234579

Title  Redesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available

DBAASP ID  13515