DCTPep ID  DCTPep03847

Peptide Name   LF Brevinin, LFB

Sequence  GLFSVVKGVLKGVGKNVSGSLLDQLKCKISGGC

Sequence Length  33

UniProt ID  Not available

PubChem CID  Not available

Origin  Animalia

Type  Native peptide

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  Cys8<--->Cys20; NCB: X1<--->Ser27

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  X(1/16)=alpha-Aminobutyrate, alpha-aminobutyric acid; X(15/25)=Acm-Cys

Chiral  L

Grand average of hydropathicity (GRAVY)  0.494

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 125
  Abs 0.1% (=1 g/l) 0.038, assuming all pairs of Cys residues form cystines
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution

Literature 1

Pubmed ID 31234333

Title  LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available

DBAASP ID  13623