This work is licensed under a Creative Commons Attribution 4.0 International License.
Ranatuerin-2Pb (1-32)
General Information
DCTPep ID DCTPep03849
Peptide Name Ranatuerin-2Pb (1-32)
Sequence SFLTTVKKLVTNLAALAGTVIDTIKCKVTGGC
Sequence Length 32
UniProt ID A9CBH5
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys26<--->Cys32
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C145H253N37O43S2
Absent amino acids EHMPQRWY
Theoretical pI 9.30
Acidic residues 1
Basic residues 4
Polar residues 13
Molecular weight (Average) 3266.95
Molecular weight (Monoisotopic) 3264.82
Common amino acids T
Net charge 3
Instability index (II) -15.32
Aliphatic index 118.75
Grand average of hydropathicity (GRAVY) 0.794
Half Life
1.9 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.038, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31242693
Title Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and its Truncated Analogues
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13625
This work is licensed under a Creative Commons Attribution 4.0 International License.