This work is licensed under a Creative Commons Attribution 4.0 International License.
AcrAP1 [S4K,H8K,S11K,S15K]
General Information
DCTPep ID DCTPep03852
Peptide Name AcrAP1 [S4K,H8K,S11K,S15K]
Sequence FLFKLIPKAIKGLIKAFK
Sequence Length 18
UniProt ID A0A0A1I6E7
PubChem CID 102602722
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C106H175N23O19
Absent amino acids CDEHMNQRSTVWY
Theoretical pI 10.60
Acidic residues 0
Basic residues 5
Polar residues 1
Molecular weight (Average) 2075.7
Molecular weight (Monoisotopic) 2074.34
Common amino acids K
Net charge 5
Instability index (II) -27.72
Aliphatic index 141.11
Grand average of hydropathicity (GRAVY) 0.856
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30268502
Title Cationicity-enhanced analogues of the antimicrobial peptides, AcrAP1 and AcrAP2, from the venom of the scorpion, Androctonus crassicauda, display potent growth modulation effects on human cancer cell lines
Doi Not available
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13648
This work is licensed under a Creative Commons Attribution 4.0 International License.