This work is licensed under a Creative Commons Attribution 4.0 International License.
AcrAP2
General Information
DCTPep ID DCTPep03853
Peptide Name AcrAP2
Sequence FLFSLIPNAISGLLSAFK
Sequence Length 18
UniProt ID A0A0A1I6N9
PubChem CID 102602721
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C95H148N20O23
Absent amino acids CDEHMQRTVWY
Theoretical pI 8.75
Acidic residues 0
Basic residues 1
Polar residues 5
Molecular weight (Average) 1938.34
Molecular weight (Monoisotopic) 1937.1
Common amino acids L
Net charge 1
Instability index (II) -0.51
Aliphatic index 141.11
Grand average of hydropathicity (GRAVY) 1.356
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25332684
Title Cationicity-enhanced analogues of the antimicrobial peptides, AcrAP1 and AcrAP2, from the venom of the scorpion, Androctonus crassicauda, display potent growth modulation effects on human cancer cell lines
Doi Not available
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13649
This work is licensed under a Creative Commons Attribution 4.0 International License.