Bac5 (1-17)[P4W]

General Information


DCTPep ID  DCTPep03944

Peptide Name   Bac5 (1-17)[P4W]

Sequence  RFRWPIRRPPIRPPFYP

Sequence Length  17

UniProt ID  P19660 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C110H163N33O19

Absent amino acids  ACDEGHKLMNQSTV

Theoretical pI  12.18

Acidic residues  0

Basic residues  5

Polar residues  1

Molecular weight (Average)  2251.71

Molecular weight (Monoisotopic)  2250.28

Common amino acids  P

Net charge  5

Instability index (II)  159.88

Aliphatic index  45.88

Grand average of hydropathicity (GRAVY)  -1.159

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  2 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 6990
  Abs 0.1% (=1 g/l) 3.104

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31692278

Title  Proline-Rich Peptides With Improved Antimicrobial Activity Against E Coli, K Pneumoniae, and A Baumannii

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  14457

DCTPep is developed by Dr.Zheng's team.