This work is licensed under a Creative Commons Attribution 4.0 International License.
Cathelicidin ModoCath5
General Information
DCTPep ID DCTPep03959
Peptide Name Cathelicidin ModoCath5
Sequence WYQLIRTFGNLIHQKYRKLLEAYRKLRD
Sequence Length 28
UniProt ID F6W4B4
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C169H265N49O40
Absent amino acids CMPSV
Theoretical pI 10.28
Acidic residues 2
Basic residues 8
Polar residues 6
Molecular weight (Average) 3623.27
Molecular weight (Monoisotopic) 3621.02
Common amino acids L
Net charge 6
Instability index (II) 4.16
Aliphatic index 101.07
Grand average of hydropathicity (GRAVY) -0.846
Half Life
2.8 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 9970
Abs 0.1% (=1 g/l) 2.752
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32194564
Title Opossum Cathelicidins Exhibit Antimicrobial Activity Against a Broad Spectrum of Pathogens Including West Nile Virus
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 14985
This work is licensed under a Creative Commons Attribution 4.0 International License.